2022 NFL playoff odds, picks, line: Cardinals vs. Rams prediction, Wild Card best bets by expert who’s 37-25

The Arizona Cardinals will try to break their late-season swoon on Monday Night Football against a familiar foe when they visit the Los Angeles Rams to close out NFL Super Wild Card Weekend 2022. The Cardinals (11-6) lost four of their last five games, while the Rams (12-5) won five of their final six. Both lost their regular-season finales entering the 2022 NFL playoffs, with Arizona falling to Seattle and L.A. being edged in overtime by San Francisco. The NFC West foes split their two matchups this season, with each team winning on the road.

Kickoff is set for 8:15 p.m. ET at SoFi Stadium. The Rams are favored by 3.5 points in the latest Cardinals vs. Rams odds from Caesars Sportsbook, while the over-under for total points scored is 49.5. Before you consider any Rams vs. Cardinals picks or 2022 NFL Playoff predictions, make sure you check out what SportsLine’s resident Rams expert, R.J. White, has to say.

CBS Sports’ Fantasy and gambling editor, White ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. It’s no surprise, as White has cashed huge twice in the world’s most prestigious football handicapping competition, the Las Vegas SuperContest. 

In addition, White has gone a stunning 37-25-1 on his last 63 picks involving the Rams. Anyone who has followed him is way up.

Now, White has set his sights on Cardinals vs. Rams and just revealed his expert NFL playoff picks and Wild Card Weekend. predictions. You can head to SportsLine now to see White’s picks. Now, here are several NFL odds for Rams vs. Cardinals: 

Cardinals vs. Rams spread: Los Angeles -3.5Cardinals vs. Rams over-under: 49.5 points  Cardinals vs. Rams money line: Los Angeles -180, Arizona +155 ARI: Cardinals are 13-3-2 against the spread as road underdogs since 2019 LAR: Rams are 11-9-1 ATS as home favorites the past three seasons

Featured Game | Los Angeles Rams vs. Arizona Cardinals

Why the Rams can cover

Los Angeles is 8-1-1 against the spread in its 10 meetings with Arizona since coach Sean McVay was hired in 2017. The Rams won by at least 10 points in eight of those. Rams quarterback Matthew Stafford is motivated to get his first playoff victory and faces a Cardinals defense that comes off its worst game of the season. It allowed 431 yards in a 38-30 loss to Seattle, and Stafford (4,886 passing yards, third in NFL) and wide receiver Cooper Kupp (NFL-high 1,947 receiving yards) torched opponents most of the season. The Cardinals started the season 7-0 but closed on a 4-6 run.

The Rams are third in the NFL in sacks with 50, and Aaron Donald (12.5), Leonard Floyd (9.5) and Von Miller (five) will be among the pursuers. The Rams have struggled to run the ball consistently, but Sony Michel (845 yards) could find holes against the NFL’s 20th-best run defense (114.8 yards per game).

Why the Cardinals can cover

Arizona looked like one of the best teams in the NFL as it started 7-0 and quarterback Kyler Murray was being touted as an early MVP candidate. But the team has struggled with injuries while going 4-6 since. However, the Cardinals have been road warriors, going 8-1 against the spread away from home this season.

Murray has dazzled at times and threw for 3,787 yards and rushed for 423. He accounted for 29 TDs despite missing three games. Wide receiver Christian Kirk (982 yards) and tight end Zach Ertz (56 receptions) have been the go-to options while injuries also have wracked the receiving corps. Chandler Jones and Markus Golden make impact plays on defense and lead a unit that has 27 takeaways (14 fumbles, first in NFL). They have combined for 21.5 sacks.

How to make NFL Playoffs or Cardinals vs. Rams picks

White has analyzed this matchup from all angles, and he is leaning Under on the point total. He also has discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing what it is, and which side of the Cardinals vs. Rams spread to back at SportsLine.

So who wins Rams vs. Cardinals on NFL Wild Card Weekend 2022? And which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see R.J. White’s Rams vs. Cardinals picks and analysis, all from the NFL expert who’s 37-25 on picks involving Los Angeles, and find out.


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