Week 15 NFL picks, odds, 2021 best bets from proven model: This five-way parlay pays out 25-1


Two playoff teams will collide when the New England Patriots and Indianapolis Colts square off Saturday at Lucas Oil Stadium. The Patriots (9-4) share the best record in the AFC with Kansas City and Tennessee but hold the No. 1 seed in the NFL playoff picture after factoring in tiebreakers. The Colts are one of five 7-6 teams in the conference but still own the No. 6 seed. Indianapolis is a 2.5-point favorite in the latest NFL odds from Caesars Sportsbook, but which side should you back with your NFL parlays and NFL bets?

The game is one of 16 on a full Week 15 NFL schedule. Other key NFL matchups include the Packers and Ravens battling in Baltimore and the Buccaneers hosting the Saints on Sunday Night Football. Before locking in any Week 15 NFL picks on those games or others, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 15. If you successfully parlay its picks, you’d be looking at a massive payout of 25-1. You can only see the model’s Week 15 NFL picks at SportsLine. 

Top Week 15 NFL picks

After simulating every game 10,000 times, the model is high on the Saints to cover as 11-point underdogs on the road against the Tampa Bay Buccaneers. Tampa Bay (10-3) is tied with Green Bay and Arizona for the best record in the NFL and holds the No. 2 seed in the NFC. New Orleans (6-7) is one of five teams tied for the third and final wild card spot in the NFC but loses the tiebreaker to Washington.

The Saints enter Sunday’s game knowing they ran all over the Buccaneers earlier this season. In the 36-27 victory in Week 8, New Orleans had five players combine for 152 rushing yards, averaging 4.8 yards per carry on 32 attempts. That was the second most rushing yards Tampa Bay has allowed this season.

How to make Week 15 NFL parlays

The model also jumped on four other matchups where it says the line is way off, including a divisional battle and a game between two teams fighting for their playoff lives. You can only see the model’s NFL Week 15 best bets and parlay at SportsLine. 

What are the model’s top Week 15 NFL picks? And which other NFL matchups should you target for a 25-1 payout? Visit SportsLine now to see the Week 15 NFL best bets from a model on a 132-96 run on its top-rated picks, and find out.



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