Chiefs vs. Chargers odds, spread: Thursday Night Football picks, prediction from top NFL model on 132-96 roll

One of the most anticipated matchups of the regular season takes place on Thursday Night Football. Patrick Mahomes and the Kansas City Chiefs (9-4) will visit Justin Herbert and the Los Angeles Chargers (8-5) to open Week 15. Both teams were victorious in Week 14 while fighting for playoff positioning. The Chiefs beat the Las Vegas Raiders 48-9, while the Chargers defeated the New York Giants 37-21. 

Kickoff from SoFi Stadium is set for 8:20 p.m. ET. Kansas City is favored by three points in the latest Chiefs vs. Chargers odds from Caesars Sportsbook, while the Over-Under is 52. Before locking in any Chargers vs. Chiefs picks, be sure to check out the NFL predictions and betting advice from the red-hot SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Chiefs vs. Chargers 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Chiefs vs. Chargers:

Chiefs vs. Chargers spread: Kansas City -3Chiefs vs. Chargers over-under: 52 points Chiefs vs. Chargers money line: Kansas City -160, Los Angeles +140 KC: Chiefs are 4-0 against the spread in their last four games overall LAC: Chargers are 5-1 ATS in their last six Thursday games

Featured Game | Los Angeles Chargers vs. Kansas City Chiefs

Why the Chiefs can cover

Travis Kelce is one of the top tight ends in the league. The Cincinnati product is second on the team with 73 receptions for 875 yards and five scores. Kelce is on pace to register his sixth straight 1,000-yard receiving season. The Ohio native is also second on the team with 67.3 receiving yards per game with 51 catches that have gone for a first down.

Kelce is a matchup nightmare for defenses due to his combination of speed, size, and hands. He stretches the middle of the field for Kansas City and has caught 10 passes of 20-plus yards downfield. Kelce has logged three games with more than 100 receiving yards. His best outing came in the Week 10 win over the Las Vegas Raiders, when the three-time First-Team All-Pro had eight catches for 119 yards.

Why the Chargers can cover

Los Angeles has one of the top young signal-callers in the league, second-year pro Justin Herbert. The Oregon product is third in the NFL in passing yards (3,822), tied for second in passing touchdowns (30), and is second in QBR (67.5). The 2020 sixth overall pick has thrown for more than 300 yards in seven games thus far. Herbert just missed that mark in the Week 14 win against the New York Giants but still played sound football.

The 2020 NFL Offensive Rookie of the Year has an absolute rocket for an arm. He unloaded a 59-yard bomb to Jalen Guyton for a score before halftime in that game.

How to make Chiefs vs. Chargers picks 

SportsLine’s model is leaning over the point total, projecting the teams to combine for 53 points. The model also says one side of the spread cashes in well over 50 percent of simulations. You can only see the model’s Chiefs vs. Chargers picks at SportsLine. 

So who wins Chargers vs. Chiefs on Thursday Night Football? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to see which side of the Chargers vs. Chiefs spread to jump on, all from the advanced model that is up almost $7,000 on its NFL picks, and find out.


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