Cardinals vs. Rams odds, spread, line: Monday Night Football picks, prediction from NFL model on 132-94 run


The Los Angeles Rams snapped a three-game losing streak with a dominant win over the Jacksonville Jaguars in Week 13 and will face their division’s top team on Monday Night Football. They’ll visit the Arizona Cardinals at State Farm Stadium to close out Week 14. The Cardinals have rattled off two consecutive double-digit wins, and Kyler Murray’s return makes them a threat to run away with the NFC West title. The Rams will be without cornerback Jalen Ramsey and tight end Tyler Higbee, who were placed on the COVID-19/reserve list.

Kickoff is slated for 8:15 p.m. ET. Arizona is favored by three points in the latest Cardinals vs. Rams odds from Caesars Sportsbook, while the Over-Under is 51. Before locking in your Rams vs. Cardinals picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 14 of the 2021 season on an incredible 132-94 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Rams vs. Cardinals 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Now, here are several NFL odds and betting lines for Rams vs. Cardinals:

Cardinals vs. Rams spread: Cardinals -3Cardinals vs. Rams over-under: 51Cardinals vs. Rams money line: Cardinals -160, Rams +140 LAR: Rams are 5-0 against the spread in their last five road games against the Cardinals ARI: Cardinals are 8-2 ATS in their last 10 games

Featured Game | Arizona Cardinals vs. Los Angeles Rams

Why the Rams can cover

The Rams needed a pick-me-up ahead of Week 13 after and gained momentum with their win. While they’re up against one of the NFL’s best teams against the spread, the hosts haven’t been strong at home. In fact, both of Arizona’s losses have come at home, and the Cardinals are just 2-3 against the spread at State Farm Field.

Los Angeles finished Week 13 ranked third in passing yards and second in passing touchdowns (30). The Rams also ranked fifth in points per game (28). While their receiving corps has been weekend by Robert Woods’ season-ending knee injury, Odell Beckham Jr. and Van Jefferson are starting to prove that they can be quality replacements alongside Cooper Kupp. Los Angeles is 5-0 straight-up and against the spread in its last five road games against Arizona. 

Why Cardinals can cover

Arizona has been one of this year’s most consistent teams against the spread. The Cardinals have covered nine times in 12 games, and only the Green Bay Packers have been more reliable. Their opponents haven’t thrived on the road this year and are just 2-4 against the spread away from home.

Arizona boasts the NFL’s third-ranked scoring offense despite not fielding a top-10 passing or rushing attack. The Cardinals average 28.6 points per game and excel at finishing drives on the ground. Only the Indianapolis Colts can top the Cardinals” total of 19 rushing touchdowns. James Conner has proved to be an effective goal-line back with 12 rushing scores, and Kyler Murray has used his speed to tally five rushing scores of his own.

How to make Rams vs. Cardinals picks 

SportsLine’s model is leaning under the point total, projecting the teams to combine for 49 points. The model also says one side of the spread cashes in well over 50 percent of simulations. You can only see the model’s Rams vs. Cardinals picks at SportsLine. 

So who wins Rams vs. Cardinals on Monday Night Football? And which side of the spread cashes well over 50 percent of the time? Visit SportsLine now to see which side of the Rams vs. Cardinals spread to jump on, all from the advanced model that is up almost $7,200 on NFL picks, and find out.



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