Monday Night Football odds, spread, line: Rams vs. 49ers picks, NFL predictions from expert on 37-19 roll


Odell Beckham Jr. will make his debut for the Los Angeles Rams when they take on the San Francisco 49ers on Monday Night Football. After being waived last week by the Browns, the 29-year-old Beckham signed with the Rams (7-2). In 88 career games with the Giants and Browns, the former 2014 first round pick has 504 receptions for 7,062 yards and 51 touchdowns. On the same day he signed with Los Angeles, the team lost receiver Robert Woods for the season to a torn ACL, placing more importance on getting Beckham up to speed quickly.

Kickoff is set for 8:15 p.m. ET. Los Angeles is a 3.5-point favorite in the latest Rams vs. 49ers odds from Caesars Sportsbook, while the Over-Under for total points scored is 50.5. Before you make any 49ers vs. Rams picks of your own, you need to see what NFL expert R.J. White has to say.

White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. It’s no surprise, as White has cashed huge twice in the world’s most prestigious football handicapping competition, the Las Vegas SuperContest.

In addition, White is an amazing 37-19-1 on his last 57 against-the-spread picks involving the Rams, returning $1,576 to $100 players. Anyone who has followed him is way up.

Now, he has locked in on Rams vs. 49ers and released a confident against-the-spread pick. Go here to see it. Here are the NFL lines and trends for 49ers vs. Rams:

Rams vs. 49ers spread: Los Angeles -3.5Rams vs. 49ers Over-Under: 50.5 pointsRams vs. 49ers money line: Los Angeles -190, San Francisco +160LAR: QB Matthew Stafford leads the league in passing yards (2,771)SF: WR Deebo Samuel ranks second in the NFL in receiving yards (882)Why the Rams can cover

The defense has demonstrated an ability to get to the quarterback, as Los Angeles leads the NFL with 28 sacks. Last week, the Rams sacked the Titans’ Ryan Tannehill three times. The defense has yet to play with sack artist Von Miller, who was acquired in a trade with the Broncos but has been out with an ankle injury. He looks likely to suit up on Monday Night Football.

In addition, Los Angeles faces a San Francisco team that has struggled at home. The 49ers enter the game on an eight-game losing streak at Levi’s Stadium, a streak that dates to Week 9 of last season. Many of the games have not been close, as the average margin of defeat in those eight games has been 9.1 points.

Why the 49ers can cover

San Francisco has dominated the series against the Rams recently. The 49ers have won the past four meetings between the teams and the past two in Santa Clara. San Francisco’s average margin of victory in those games is 6.8 points.

In addition, the 49ers face Rams quarterback Matthew Stafford, who is coming off his worst game of the season. In the Sunday night loss to the Titans, Stafford was sacked a season-high five times. He also had his first multi-interception game of the season and averaged 6.1 yards per attempt, his fewest in a game this season.

How to make Rams vs. 49ers picks

White has analyzed this matchup and while we can tell you he’s leaning Under the total, he has discovered a crucial x-factor that makes one side of the spread a must-back. He’s sharing it only at SportsLine.

Who wins 49ers vs. Rams on Monday Night Football? And what critical factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the 49ers vs. Rams spread you should jump on, all from the top NFL expert who is 37-19 on against-the-spread picks involving the Rams, and find out.



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